Depression is a chronic medical illness that causes a persistent feeling of sadness or loss of interest, and can lead to a range of emotional and physical problems. The condition may be referred to as major depression, clinical depression, or major depressive disorder (MDD). People with depression are often at increased risk of heart disease, diabetes, asthma, and obesity.

Depression and Related Conditions

Bipolar disorder
Causes swings between period of depression and elation. Bipolar disorder was previously called manic-depression.
Refers to chronic symptoms that are not disabling, but cause lower energy and productivity. Dysthmia symptoms can change in intensity, but generally last for several months.
Major depressive disorder
Interferes with the ability to perform daily activities. It is the leading cause of disability in the developed world, and each year about 19 million adults in America suffer from depression.

Depression Treatments and Trials

Doctors currently treat clinically depressed people with a variety of more than 20 Food and Drug Administration-approved medications, which can reduce symptoms for about two-thirds of those treated. UT Southwestern Medical Center physicians offer patients access to traditional treatments as well as the opportunity to participate in clinical trials for the latest innovations in depression treatment.

Psychosocial Research and Depression Clinic

Our Psychosocial Research and Depression Clinic seeks to understand how psychosocial factors and treatments influence the course of mood and related disorders. The goal is to create new knowledge and treatments that will reduce the suffering of those with recurrent atypical depression, using cognitive therapy for preventing relapses, and ultimately, through interdisciplinary collaboration, produce a cure.

The Clinic was established in 1989 for the express purposes of:

  • Developing better and sustainable interventions
  • Disseminating findings that promote a better understanding of depression, psychotherapy, and the impact of psychosocial factors on illness and recovery through collaboration, presentation, publication, teaching, technological advances, and community outreach
  • Learning about the etiology, maintenance, course, and treatment of mood and related disorders, with special emphasis on the role of psychosocial factors and psychotherapy

In short, we evaluate the role of psychosocial (i.e., psychological, attitudinal, social, and interpersonal) factors and interventions on the course of depression.

Our Depression Specialists

Our interdisciplinary team enjoys international and national collaboration and includes psychologists, psychiatrists, biostatisticians, research associates, private practitioners, nurses, physician’s assistants, trainees, and administrators. 

Request an Appointment

To schedule an appointment at UT Southwestern's facilities in Dallas or for more information about our depression services, request an appointment or call 214-645-8300.