Treatment Options

UT Southwestern Medical Center is a leader in the research and treatment of genetic disorders. We use a multidisciplinary approach to treat the individual conditions caused by the disorders. Our adult and pediatric programs offer consultation, evaluation, counseling, and treatment for inherited diseases and known or suspected genetic conditions.

While there’s no cure for Osteogenesis imperfecta, our physicians work with our patients to prevent deformities and fractures and to help them function as independently as possible.

Treatments for preventing or correcting symptoms may include:

  • Assistive devices, such as wheelchairs, braces, and other custom-made equipment
  • Care of fractures
  • Dental procedures
  • Physical therapy
  • Rodding, which is the insertion of a metal bar the length of a long bone to stabilize it and prevent deformity
  • Surgery

Management of OI

Management includes focusing on preventing or minimizing deformities and maximizing your functional ability at home and in the community. Both nonsurgical or surgical management options are available.

Nonsurgical interventions may include one or more of the following:

  • Braces and splints to prevent deformity and promote support or protection
  • Medications
  • Physical therapy
  • Positioning aids to help sit, lie, or stand
  • Psychological counseling

Surgical interventions may help manage these conditions:

  • Bowing of bone
  • Fractures
  • Heart problems
  • Scoliosis, which is a lateral or sideways curvature and rotation of the backbones, giving the appearance that the person is leaning to one side

Surgery may also be considered to maintain the ability to sit or stand.