Cancer research
Mahboubeh Papari; Bonnie Gao, Ph.D.; Victor Stastny; John Minna, M.D.; and Adi Gazdar, M.D., are among scientists working to advance new therapies from discovery to drug development.

The special mission of UT Southwestern Medical Center's Harold C. Simmons Comprehensive Cancer Center is to bring new knowledge and technology into the fight against cancer through the work of our scientific programs.

Scientific Programs

At Simmons Comprehensive Cancer Center, five complementary scientific programs serve as vehicles for discovery:

Within these programs, it’s people who drive growth and progress.

The Cancer Center’s nearly 250 members are affiliated with 40 departments or centers across UT Southwestern and represent a wealth of opportunity to blend basic knowledge with translational and clinical pursuits.

Funding Sources

Funding from a wide range of sources fuels a host of scientific investigations, including collaborative, cross-disciplinary efforts with the potential to broadly impact the state of cancer knowledge and care. The work helps thousands of patients every year at Simmons Comprehensive Cancer Center clinics, including a growing number of people receiving the latest in cancer care through clinical trials.

Simmons Comprehensive Cancer Center currently has 40 investigator-initiated clinical trials – more than any other cancer center in North Texas.

In the Community

Simmons Comprehensive Cancer Center is also pushing forward and outward into the community, building and improving laboratories to disseminate discoveries related to cancer prevention and detection, especially among the medically underserved. 

For example, a new, NCI-funded community partnership called PROSPR (Population-based Research Optimizing Screening through Personalized Regimens) is exploring how best to ensure regular colon cancer screenings. 

In addition, a robust cancer genetics program is reaching out to ensure that patients and families with an elevated hereditary risk of colon and uterine cancers, as well as those with gene mutations linked to breast and ovarian cancers, are alerted and closely monitored. 

Such wheels of progress promise to generate advances for decades to come. Those advances will improve the state of science not just at Simmons Comprehensive Cancer Center, but also throughout Texas and the nation.