Deciphering androgen receptor signaling in primary prostate tissue

Summary

We will use the targeted biopsies from MRi TRuS fusion as these biopsies have a very high positive yield. Typically, 18-20 biopsies are performed including 4-6 biopsies of the targeted lesions are performed during clinic TRuS biopsies. in our proposal, we would need only 2 additional biopsies from the targeted lesions that would be processed independently of the other biopsies.

Participant Eligibility

Any male patient between the ages of 18 and 89 undergoing MRI TRUS fusion prostate biopsy for an elevated PSA with a clearly targetable lesion is eligible to enter into the study.