Gestational Trophoblastic Disease

Gestational trophoblastic disease (GTD) is a group of rare tumors that grow inside a woman’s uterus when she is pregnant. These tumors develop in the cells that form the placenta, which surrounds an embryo during pregnancy.

Types of Gestational Trophoblastic Diseases

One type of GTD is hydatidiform moles, which are mostly benign. Sometimes they can develop into invasive moles, or, rarely, into choriocarcinoma, which spreads quickly. The good news is these moles are highly sensitive to chemotherapy and have a very good prognosis.

Another type of GTD is trophoblasts, which typically do not spread to other areas of the body, but they can grow into the muscle layer of the uterus. These tumors are usually surgically removed.

In most cases, the treatment produces a complete cure.