Phase I Cancer Clinical Trials

Simmons Cancer Center’s Phase I Clinical Trials Team offers new, targeted therapies for cancer patients. We match the trial with the patient to optimize the opportunity for benefit. We have selected a refined group of cutting-edge studies. Phase I clinical trials enroll a few dozen patients per trial, test the best dose and schedule, and look for side effects, drug levels in blood and tissue, and patient response.


Patients must have cancer that has not responded to standard therapy or for which no curative therapy is known. The patient must be able to travel to Dallas, Texas, on a regular basis and be out of bed at least 50% of the day. There may be other criteria for participation in particular studies.

Why Choose UTSW?

Simmons Cancer Center is the only NCI-designated Cancer Center in North Texas and sees approximately 5,000 new patients per year. In addition to experimental therapy studies, we offer patients multidisciplinary care provided by subspecialists who are focused on a particular type of cancer.

Request To Participate

For more information about Phase I cancer clinical trials at Simmons Cancer Center or to make an appointment with a member of our Phase I Clinical Trials Team, please call 214-648-1242 and you will speak with either Roberto Torres or Adrian Avila.

From left to right: Diadria Thomas, Roberto Torres, Adrian Avila, Arthur Frankel, M.D., Oluwatomilade Fatunde, Connie Cervantes, Mieshia Beamon (below), Amber Summers (above)

When speaking with a team member about treatment, please have the following information ready:

  • Patient name, telephone number, and insurance information
  • Referring physician's name, office address, telephone, and fax numbers
  • Diagnosis
  • Date of diagnosis
  • How the diagnosis was made (physical exam, biopsy, other)
  • What treatment, if any, has taken place
  • Over what time period the treatment has occurred
  • Specific medical and pathology reports may also be requested for review before your first visit

Our team will work with you or your referring physician to expedite your first appointment.