Peritoneal Cancer

Peritoneal cancer is a rare cancer that develops in the peritoneum – a thin layer of cells that lines the inside wall of the abdomen and covers the uterus, bladder, stomach, intestines, and rectum.

If the cancer starts in the peritoneum, which is rare, it’s called primary epithelial peritoneal cancer. Another type of primary peritoneal cancer is peritoneal malignant mesothelioma

It’s more common for cancer cells to begin somewhere else in the body and spread to the peritoneum. This is known as secondary peritoneal cancer. This is usually related to the spread to the peritoneum of primary abdominal cancers such as appendix cancer, colon cancer, gastric cancer, and ovarian cancer, among others. 

Whether your peritoneal cancer starts in the peritoneum or spreads from somewhere else, it is considered advanced (stage IV) once it’s in the peritoneum and may be referred to as peritoneal carcinomatosis.

Program Highlights

As an academic medical center and the only cancer program in North Texas designated by the National Cancer Institute, UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center has a team of experts who specialize in peritoneal cancer.

Our multidisciplinary Peritoneal Malignancies and HIPEC Program provides the most advanced treatments , including cytoreductive surgery to remove tumors in the abdomen combined with hyperthermic intraperitoneal chemotherapy (HIPEC). HIPEC is offered for patients with primary (epithelial and mesothelioma) and secondary peritoneal cancer from gastrointestinal tumors. This is a complex and highly specialized treatment that’s only offered at top cancer centers.

How We Can Help

At UT Southwestern, our peritoneal cancer patients receive:

  • Treatment plans tailored to each individual, including access to treatment not offered at other medical centers
  • Support services such as cancer nutrition and rehabilitation, to help improve your quality of life
  • Genetic counseling, since some primary peritoneal cancers are caused by inherited gene mutations

Meet the Team

Our UT Southwestern physicians who treat peritoneal cancer include:

Request an Appointment

To schedule a visit with a peritoneal cancer specialist at UT Southwestern’s facilities in Dallas or to learn more about our services, request an appointment or call 214-645-8300.


Surgical Oncology Clinic
Seay Biomedical Building
2201 Inwood Road
2nd Floor
Dallas, Texas 75390