Bone Marrow Transplant

Bone marrow transplants are often used in conjunction with other therapies to treat patients with certain cancers of the blood, bone marrow, and lymph nodes, as well as some types of blood and immune disorders.

Also known as stem cell transplants, bone marrow transplants transfer normal mature stem cells from adults into patients who need them.

No. 1 Survival Rate

The UT Southwestern Bone Marrow Transplant program is recognized as one of the country’s top programs of its kind and stands out among regional competition for hematologic malignancies. With more than 1,000 transplants to date, it is No. 1 in North Texas for one-year survival rates for allografts and is a National Center of Excellence for all the major national insurance carriers.

We also are the only transplant program in North Texas associated with a National Cancer Institute-designated cancer center.

In addition, UT Southwestern’s Bone Marrow Transplant program is accredited by the Foundation for the Accreditation of Cellular Therapy, which recognizes bone marrow transplant programs for top quality patient care in cellular therapies. We are also an affiliate of the National Marrow Donor Program.

Experts Who’ve Performed More Than 1,000 Transplants

Our experienced and highly skilled team has performed more than 1,000 bone marrow transplants – both autologous (using a patient’s own cells) and allogeneic (using donor cells) – ranging in adults from early adulthood to those in their early 70s.

The team also performs haploidentical and cord blood transplantation, making transplantation a viable option for many more patients than in the past.

In addition to state-of-the-art technologies and facilities, the program also offers a range of therapies that support these procedures.

Our experts include:

How Bone Marrow Transplantation Is Performed

Many people think that a bone marrow transplant involves major surgery, but it’s actually performed much like a blood transfusion: Bone marrow cells are introduced to the blood with growth factor injections and then collected from the bloodstream. They are then given to the patient by an infusion into the bloodstream.

The infused cells are hematopoietic stem cells, which help the body produce new blood and immune cells. This is necessary for patients who have received high doses of chemotherapy (and sometimes radiation), which can help manage or even cure cancer but also can suppress the body’s ability to make blood.

Our Unique Approach

“We manage patients at all stages of their care, from initial diagnosis through an individualized treatment plan,” says the program’s Director, Robert Collins, M.D. “Our physicians are true experts in the field, and all have particular disease focuses to ensure we are providing the most effective and up-to-date care possible.”

Therefore, receiving care at UT Southwestern means you have access to therapies that aren’t available at every hospital. We offer an option for bone marrow transplant in which we manipulate cells before they are transplanted, allowing us to engineer the transplant graft in a way that removes cells that could be harmful to the recipient and cause graft-versus-host disease.

In addition, we are able to transplant immune cells that have been specifically engineered using gene therapy to attack a patient’s cancer cells but that also can be “turned off” if they start causing toxic side effects.

This approach, led by transplant specialist Madhuri Vusirikala, M.D., represents a life-saving alternative for patients with severe forms of blood cancers.

Request an Appointment

To schedule an appointment with a bone-marrow transplant expert, request an appointment or call 214-645-8300.