About Us

The Peter O’Donnell Jr. Brain Institute has an ambitious goal: To better understand the basic molecular workings of the brain and apply those discoveries to the prevention and treatment of brain and spine diseases and injuries.

By bringing together transformative research and patient-centered care, our objective is to improve the lives of patients today and those of generations to come. We’re aggressively tackling neurological illnesses and conditions in their various forms through:

  • Developing and exploring groundbreaking new treatments
  • Leading cutting-edge research to determine the biological basis for neurological and psychiatric disorders
  • Advancing patient-centered care for all types of brain and spine disorders and injuries

This means new possibilities to treat strokes, brain aneurysms, brain tumors, Alzheimer’s Disease, Parkinson’s Disease, epilepsy, traumatic brain injury and concussion, multiple sclerosis, depression, autism, degenerative spine conditions, and many other neurological, and psychiatric disorders that exact a tremendous toll on individuals, families, and society.

An Extraordinary Team

Confronting an extraordinary challenge takes an extraordinary team.

The O’Donnell Brain Institute has assembled the largest team of researchers and physicians in North Texas focused on neurosciences, including experts – many of them internationally recognized – in:

  • Neurosciences
  • Neurosurgery
  • Neurology and Neurotherapeutics
  • Physical Medicine and Rehabilitation
  • Psychiatry
  • Neuroradiology
  • Otolaryngology
  • Orthopaedic spine
  • Neuro-ophthalmology
  • Neuropathology
  • And many other disciplines within UT Southwestern

Related Endowed Centers

Along with the departments, the O’Donnell Brain Institute is connected with the following UT Southwestern centers:

  • Texas Institute for Brain Injury and Repair
  • Center for Alzheimer's and Neurodegenerative Diseases
  • Paul M. Bass Center for Neurosurgical Innovation
  • Effie Marie Cain Alzheimer's Research Center
  • Cain/Denius Comprehensive Center in Mobility Research
  • Crystal Charity Ball Center for Pediatric Brain and Neurological Diseases
  • Center for Depression Research and Clinical Care
  • Gill Center for Research on Brain Cell Communication
  • Beatrice Menne Haggerty Center for Research on Brain Injury and Repair in Strokes
  • Hamon Center for Regenerative Science and Medicine
  • Dorothy L. and John P. Harbin Center for Alzheimer's Disease Research
  • Kimberly-Clark Center for Physical Medicine and Rehabilitation
  • Erma Lowe Center for Alzheimer's Disease Research
  • Mobility Foundation Center for Rehabilitation Research
  • Center for Translational Neurodegeneration Research
  • Pogue Family Center for Advanced Brain Imaging in Alzheimer's Disease
  • Vincent Prothro Center for Research in Basic Neuroscience
  • Robert D. Rogers Advanced Comprehensive Stroke Center
  • Sarah M. and Charles E. Seay Center for Basic & Applied Research in Psychiatric Illness
  • Harold and Annette Simmons Comprehensive Center for Research and Treatment of Brain and Neurological Disorders
  • Annette G. Strauss Center in Neuro-Oncology
  • Kent Waldrep Foundation Center for Basic Research on Nerve Growth and Regeneration
  • Jean Walter Center for Research in Movement Disorders
  • Winspear Family Special Center for Research on the Neuropathology of Alzheimer's Disease

By weaving together neurosciences efforts across multiple departments, including researchers and clinicians, we are accelerating progression in injury prevention, novel brain preservation strategies, and restoration of brain function lost by disease and injury.

Taking the Next Steps

UT Southwestern has a long history of involvement in the neurosciences through its leading-edge research, advanced technology, and expertise in clinical care, with many milestones along the way. In fact, 2015 was a landmark year in our development. The University of Texas Board of Regents approved the establishment of a Brain Institute at UT Southwestern, and it was announced that Peter O’Donnell, Jr., provided $36 million to support our commitment.

The O’Donnell Brain Institute is the next leap forward in meeting one of the greatest medical challenges of our time – understanding and mastering the complexities of the brain to enhance human health.

We invite you to learn more about the O’Donnell Brain Institute and the life-changing and life-saving activities underway in our laboratories and clinics.

The future of brain and spine care is, for us, top of mind.